In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results Trial Scorecard: REDEFINE 1 and 2 Type 2 diabetes: Combo of semaglutide and cagrilintide reduces blood sugar and leads to weight loss Structural and mechanistic insights into dual activation of cagrilintide in amylin and calcitonin receptors Acta Pharmacologica Sinica
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semaglutide and cagrilintide Weight Loss Efficacy of Cagrilintide and Semaglutide