The MTHFR gene mutation is the world's biggest translation problem. If you're born with it, your body can't understand the language of standard vitamins. Even if you ingest them, they'll pass through, MTHFR Gene Spotlight Genomind B vitamin polymorphisms and behavior: Evidence of associations with neurodevelopment, depression, schizophrenia, bipolar disorder and cognitive decline ScienceDirect MTHFR Gene Mutation & How to Manage It Amy Myers MD AMMD