Does Glutathione IV and Vitamin Supplements with Glutathione Have Any Negative Side Effects? Skin safety should always come first. The Philippine Dermatological Society reminds the public that intravenous glutathione must not be used for skin whitening. It has weak evidence of effectiveness and carries FDA Advisory No. 2019 182*** UNSAFE USE OF GLUTATHIONE AS SKIN LIGHTENING AGENT The Food and Drug Administration (FDA) warns the public on the dangers associated with the use of injectable lightening agents Glutathione as a skin whitening agent: Facts, myths, evidence and controversies Indian Journal of Dermatology, Venereology and Leprology