Why patients taking enzyme Inducers and patients with anorexia nervosa experience higher risk of paracetamol toxicity?? Acetaminophen (Paracetamol) is extensively metabolized by the liver via three main hepatic pathways: glucuronidation, sulfation, Problem 2: N acetyl para benzoquinone (NAPQI) is an oxidized metabolite of acetaminophen formed in the liver. NAPQI is converted into an acetaminophen glutathione conjugate, a non toxic metabolite Acute acetaminophen paracetamol toxicity Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine YouTube
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