Pernicious Anemia: Definition, Symptoms, Causes & Treatment High dose vitamin B12 supplements can sometimes cause side effects, including headache, nausea, vomiting, mild diarrhea, itching, skin rash, tiredness, weakness, or tingling in the hands and feet. OC: The Truth About B12 Injections: Benefits, Cost & How They Work Vitamin B12 Injections: Good or Bad?
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