In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results CagriSema vs Tirzepatide: 23% Weight Loss in Phase 3 Trial CagriSema Weight Loss Injection Results Safety UK Update Weight loss with GLP 1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans: Cell Reports Medicine
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